Primary Identifier | MGI:3576783 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 268465 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Predicted to contribute to crossover junction DNA endonuclease activity. Predicted to be involved in DNA metabolic process and mitotic intra-S DNA damage checkpoint signaling. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Located in heterochromatin. Is expressed in several structures, including adrenal medulla; cerebral cortex; respiratory system; sensory organ; and skeleton. Orthologous to human EME1 (essential meiotic structure-specific endonuclease 1). PHENOTYPE: Mice homozygous for a null allele exhibit normal survival. [provided by MGI curators] |