| Primary Identifier | MGI:1343087 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 18604 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in several processes, including glucose homeostasis; insulin receptor signaling pathway; and regulation of small molecule metabolic process. Acts upstream of or within regulation of calcium-mediated signaling. Located in mitochondrion. Part of pyruvate dehydrogenase complex. Is expressed in aorta; cerebral cortex; cerebral cortex subventricular zone; heart; and liver. Orthologous to human PDK2 (pyruvate dehydrogenase kinase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased muscle contractile force. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
