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Protein Coding Gene : Tac4 tachykinin 4

Primary Identifier  MGI:1931130 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  93670
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables receptor ligand activity; substance K receptor binding activity; and substance P receptor binding activity. Involved in positive regulation of cytosolic calcium ion concentration and tachykinin receptor signaling pathway. Acts upstream of or within positive regulation of saliva secretion. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including adrenal gland; genitourinary system; gut; hemolymphoid system gland; and integumental system. Orthologous to human TAC4 (tachykinin precursor 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased pro-B cells without an increase in mature B cells. [provided by MGI curators]
  • synonyms:
  • hemokinin I (HK-1),
  • expressed sequence AW489379,
  • MGI:2144537,
  • PPT-C,
  • AW489379,
  • tachykinin 4,
  • Tac4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For