| Primary Identifier | MGI:96186 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 15413 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryonic skeletal system morphogenesis; endothelial cell differentiation; and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; lung; and nervous system. Orthologous to human HOXB5 (homeobox B5). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile but exhibit a rostral shift of the shoulder girdle resulting in altered position of the forelimbs, and show variable anteriorizing homeotic transformations of cervicothoracic vertrebrae C6 through T1. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
