Primary Identifier | MGI:3619064 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 723893 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to alcohol; cellular response to lipopolysaccharide; and miRNA-mediated post-transcriptional gene silencing. Is expressed in several structures, including forelimb; metanephros; pinna; and trunk. Orthologous to human MIR10A (microRNA 10a). PHENOTYPE: Mice homozygous for a targeted deletion are viable with no observed pathologies. Mice homozygous for a knock-out allele exhibit increased frequency with of high-grade dysplasia and higher incidence of tubule-villous adenomas in Apcmin heterozygotes. [provided by MGI curators] |