Primary Identifier | MGI:1925723 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 78473 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SH2 domain binding activity; protein kinase binding activity; and protein phosphatase binding activity. Acts upstream of or within positive regulation of cell adhesion and protein localization to plasma membrane. Located in cell-cell junction; cytosol; and plasma membrane. Part of T cell receptor complex. Orthologous to human SKAP1 (src kinase associated phosphoprotein 1). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit decreased T cell aggregation, adhesion and proliferation following stimulation. [provided by MGI curators] |