| Primary Identifier | MGI:1934234 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 108083 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol kinase activity; protein homodimerization activity; and purine ribonucleoside triphosphate binding activity. Involved in autophagosome-lysosome fusion and regulation of autophagy. Acts upstream of or within phosphatidylinositol metabolic process. Predicted to be located in autophagosome and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in head bone; nervous system; and sensory organ. Orthologous to human PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase type 2 beta). PHENOTYPE: Mice homozygous for disruptions in this gene are smaller than normal with less body fat and an increased sensitivity to insulin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
