| Primary Identifier | MGI:109656 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 16796 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin filament binding activity. Predicted to be involved in monoatomic ion transport. Located in cytoplasm and focal adhesion. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and hemolymphoid system gland. Orthologous to human LASP1 (LIM and SH3 protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced histamine-stimulated gastric acid secretion and enlarged heart and testes on a mixed background. Mice homozygous for a transgene insertion exhibit abnormal tail vertebrae with scoliosis, transient spina bifida occulta, and a bent tail. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
