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Protein Coding Gene : Fbxl20 F-box and leucine-rich repeat protein 20
Primary Identifier  MGI:1919444 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  72194
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in regulation of protein catabolic process at presynapse, modulating synaptic transmission and regulation of synaptic vesicle exocytosis. Acts upstream of or within behavioral fear response. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including adrenal gland; brain; genitourinary system; gut; and respiratory system. Orthologous to human FBXL20 (F-box and leucine rich repeat protein 20).
PHENOTYPE: Mice homozygous for a null allele exhibit some embryonic lethality, shortened lifespans, decreased body size and altered CNS synaptic transmission. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2610511F20 gene,
  • F-box and leucine-rich repeat protein 20,
  • Scr,
  • MGI:2144684,
  • MGI:3034930,
  • expressed sequence AI849362,
  • AI849362,
  • C86145,
  • AL117906,
  • expressed sequence AL117906,
  • 2610511F20Rik,
  • Fbl2,
  • RIKEN cDNA 4632423N09 gene,
  • expressed sequence C86145,
  • Scrapper,
  • MGI:2144301,
  • 4632423N09Rik,
  • Fbxl20
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