Primary Identifier | MGI:1344385 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 23989 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone acetyltransferase activity; nuclear thyroid hormone receptor binding activity; and transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance and transcription by RNA polymerase II. Part of mediator complex. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and retina. Orthologous to human MED24 (mediator complex subunit 24). PHENOTYPE: Homozygous mutant mice die prior to birth exhibiting abnormal heart development, neural tube defects, and anemia. [provided by MGI curators] |