| Primary Identifier | MGI:2179723 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 192160 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and ubiquitin protein ligase binding activity. Acts upstream of or within intracellular mRNA localization. Located in cytoplasm and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Orthologous to human CASC3 (CASC3 exon junction complex subunit). PHENOTYPE: Homozygous null mice show decreased embryo size and embryonic lethality. Homozygotes for one knock-out allele exhibit absent primitive node and head folds, and failure to gastrulate. Homozygotes for a hypomorphic allele show delayed fetal growth and limb development and complete lethality during fetal growth through weaning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
