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Protein Coding Gene : Krt10 keratin 10
Primary Identifier  MGI:96685 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  16661
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables cytoskeletal protein binding activity. Involved in positive regulation of epidermis development. Acts upstream of or within several processes, including cellular response to calcium ion; intermediate filament organization; and keratinocyte development. Located in cytoplasm and keratin filament. Is active in cornified envelope. Is expressed in several structures, including alimentary system; lower urinary tract; penis; sensory organ; and skin. Used to study epidermolytic hyperkeratosis. Human ortholog(s) of this gene implicated in epidermolytic hyperkeratosis and epidermolytic hyperkeratosis 2. Orthologous to human KRT10 (keratin 10).
PHENOTYPE: Mutations may result in hyperkeratosis and blistering of the skin. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-11640,
  • Krt10,
  • Krt-1.10,
  • keratin 10,
  • D130054E02Rik,
  • MGI:2441944,
  • K1C1,
  • MGD-MRK-11630,
  • cytokeratin 10,
  • keratin complex 1, acidic, gene 10,
  • RIKEN cDNA D130054E02 gene,
  • Krt1-10,
  • suprabasal cytokeratin 10,
  • keratin complex 1 gene 10,
  • K10
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Trail: ProteinCodingGene




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