| Primary Identifier | MGI:101925 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 16663 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable structural molecule activity. Involved in regulation of translation in response to stress. Predicted to be located in extracellular exosome and intermediate filament cytoskeleton. Predicted to be active in keratin filament. Is expressed in several structures, including alimentary system; lower urinary tract; salivary gland primordium; sensory organ; and skin. Used to study white sponge nevus. Human ortholog(s) of this gene implicated in white sponge nevus 2. Orthologous to human KRT13 (keratin 13). PHENOTYPE: Mice homozygous for a null allele exhibit white sponge nevus-like phenotype in several tissues including the tongue, buccal mucosa, and esophagus showing thickened epithelium, loss of keratohyalin granules, and disorganized keratin layer. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
