Primary Identifier | MGI:1338755 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 11858 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within positive regulation of collateral sprouting. Predicted to be located in early endosome. Predicted to be active in cytosol and plasma membrane. Is expressed in brain. Orthologous to human RND2 (Rho family GTPase 2). PHENOTYPE: Oligodenddrocyte-specific knock-out mice exhibit decreased myelin thickness at the onset of myelination but increased myelin thickness in the later period. [provided by MGI curators] |