| Primary Identifier | MGI:1919599 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 72349 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein tyrosine/serine/threonine phosphatase activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity; and regulation of focal adhesion assembly. Acts upstream of or within protein dephosphorylation. Is active in axonemal microtubule doublet inner sheath and sperm flagellum. Is expressed in central nervous system; dorsal root ganglion; retina; and urinary system. Orthologous to human DUSP3 (dual specificity phosphatase 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased hemoglobin content and angiogenesis in Matrigel plugs and aortic explants. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
