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Protein Coding Gene : Hexim1 hexamethylene bis-acetamide inducible 1
Primary Identifier  MGI:2385923 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  192231
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including 7SK snRNA binding activity; P-TEFb complex binding activity; and cyclin-dependent protein serine/threonine kinase inhibitor activity. Acts upstream of or within heart development and negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including branchial arch; embryo mesenchyme; heart and pericardium; hindgut dorsal mesentery; and sensory organ. Orthologous to human HEXIM1 (HEXIM P-TEFb complex subunit 1).
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit prenatal lethalilty associated with dilated cardiomyopathy. [provided by MGI curators]
  • synonyms:
  • Hexim1,
  • hexamethylene bis-acetamide inducible 1,
  • MGI:1925754,
  • RIKEN cDNA 7330426E13 gene,
  • cardiac lineage protein 1,
  • CLP-1,
  • HIS1,
  • 7330426E13Rik,
  • Clp1
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