| Primary Identifier | MGI:98955 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 22415 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein domain specific binding activity. Involved in positive regulation of Wnt signaling pathway. Acts upstream of or within several processes, including axis specification; embryonic morphogenesis; and regulation of extent of cell growth. Located in extracellular matrix. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo ectoderm; and sensory organ. Human ortholog(s) of this gene implicated in tetraamelia syndrome 1. Orthologous to human WNT3 (Wnt family member 3). PHENOTYPE: Homozygous mutants develop to the egg cylinder stage, but fail to form a primitive streak, mesoderm, or node, and die by embryonic day 10.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
