| Primary Identifier | MGI:3045264 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 237958 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables aspartic endopeptidase activity, intramembrane cleaving and molecular adaptor activity. Involved in several processes, including acrosome assembly; fusion of sperm to egg plasma membrane involved in single fertilization; and protein stabilization. Located in endoplasmic reticulum membrane. Orthologous to human SPPL2C (signal peptide peptidase like 2C). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased testis weight, decreased number of elongated spermatids, asthenozoospermia, and decreased litter size in matings of male and female homozygotes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
