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Protein Coding Gene : Ddx42 DEAD box helicase 42
Primary Identifier  MGI:1919297 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  72047
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in U2-type prespliceosome assembly; protein localization; and regulation of apoptotic process. Predicted to be located in cytosol and nuclear speck. Predicted to be part of U2-type prespliceosome. Predicted to be active in nucleus. Orthologous to human DDX42 (DEAD-box helicase 42).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit defects in chorion and trophoblast layer formation and complete embryonic lethality during organogenesis. [provided by MGI curators]
  • synonyms:
  • MGI:1925772,
  • expressed sequence AW556242,
  • AW556242,
  • MGI:2144573,
  • RIKEN cDNA B430002H05 gene,
  • MGI:2144523,
  • B430002H05Rik,
  • SF3b125,
  • RIKEN cDNA 1810047H21 gene,
  • 1810047H21Rik,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 42,
  • AW319508,
  • Ddx42,
  • expressed sequence AW319508,
  • DEAD box helicase 42
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