Primary Identifier | MGI:2685731 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 380732 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in mast cell degranulation and negative regulation of mast cell activation. Predicted to be located in plasma membrane. Is expressed in adrenal gland; stomach; and testis. Orthologous to human MILR1 (mast cell immunoglobulin like receptor 1). PHENOTYPE: Mice homozygous for a null allele have decreased mast cell degranulation and an increased susceptibility to type I hypersensitivity reaction. [provided by MGI curators] |