Primary Identifier | MGI:1338824 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 19739 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Acts upstream of or within dark adaptation and light adaption. Is active in glutamatergic synapse; postsynaptic density membrane; and presynaptic membrane. Is expressed in several structures, including central nervous system and retina. Human ortholog(s) of this gene implicated in bradyopsia 1. Orthologous to human RGS9 (regulator of G protein signaling 9). PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile; however, relative to wild-type, homozygous null photoreceptors display abnormally retarded recovery of their light responses, and slowed rates of GTP hydrolysis by transducin. [provided by MGI curators] |