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Protein Coding Gene : Rnf157 ring finger protein 157

Primary Identifier  MGI:2442484 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  217340
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of apoptotic process; positive regulation of dendrite extension; and protein ubiquitination. Predicted to be located in cell body. Predicted to be active in cytoplasm. Is expressed in future spinal cord. Orthologous to human RNF157 (ring finger protein 157).
PHENOTYPE: The gene supports neuronal survival and dendrite growth and maintenance and knockdown with siRNA induces apoptosis in neuronal tissues. [provided by MGI curators]
  • synonyms:
  • MGI:1917169,
  • 2610036E23Rik,
  • ring finger protein 157,
  • RIKEN cDNA A130073L17 gene,
  • A130073L17Rik,
  • RIKEN cDNA 2610036E23 gene,
  • Rnf157

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

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Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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