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Protein Coding Gene : Engase endo-beta-N-acetylglucosaminidase
Primary Identifier  MGI:2443788 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  217364
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Acts upstream of or within protein deglycosylation. Predicted to be located in cytosol. Orthologous to human ENGASE (endo-beta-N-acetylglucosaminidase).
PHENOTYPE: Mice homozgyous for knock-out alleles of this gene and Ngly1 exhibit restored endoplasmic reticulum (ER)-associated degradation (ERAD) process compared with MEFs lacking only Ngly1. [provided by MGI curators]
  • synonyms:
  • Engase,
  • endo-beta-N-acetylglucosaminidase,
  • RIKEN cDNA D230014K01 gene,
  • D230014K01Rik
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