| Primary Identifier | MGI:88289 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12416 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity and methylated histone binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in euchromatin; heterochromatin; and nucleus. Part of PcG protein complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; immune system; and retina nuclear layer. Human ortholog(s) of this gene implicated in 46,XY sex reversal 5. Orthologous to human CBX2 (chromobox 2). PHENOTYPE: Mutations cause malformations of the axial skeletal, reduced viability, poor growth and male to female sex reversal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
