| Primary Identifier | MGI:1353589 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 30951 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables single-stranded RNA binding activity and ubiquitin-protein transferase activator activity. Predicted to be involved in positive regulation of cell population proliferation; positive regulation of collagen biosynthetic process; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within heterochromatin formation. Located in heterochromatin and nucleus. Part of PRC1 complex. Is expressed in several structures, including brain. Orthologous to human CBX8 (chromobox 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired MLL-AF9 transformation but are otherwise viable with normal hematopoiesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
