Primary Identifier | MGI:2444688 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 338371 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables endodeoxyribonuclease activity, producing 5'-phosphomonoesters and magnesium ion binding activity. Involved in DNA repair. Predicted to be located in cytoplasmic stress granule. Predicted to be active in cytoplasm and nucleolus. Orthologous to human ENDOV (endonuclease V). PHENOTYPE: Mice homozygous for a null allele exhibit fewer and smaller liver tumors when chemically-induced. [provided by MGI curators] |