Primary Identifier | MGI:1197518 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 11302 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein tyrosine kinase activity. Acts upstream of or within brain development; neuron apoptotic process; and peptidyl-tyrosine autophosphorylation. Predicted to be located in several cellular components, including dendrite; growth cone; and perinuclear region of cytoplasm. Is expressed in brain; corpus callosum; spinal cord; spinal cord gray matter; and spinal cord white matter. Orthologous to human AATK (apoptosis associated tyrosine kinase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased brain size, longer axons and fewer neurites. [provided by MGI curators] |