Primary Identifier | MGI:95485 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 14104 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fatty acid synthase activity. Involved in ether lipid biosynthetic process; mammary gland development; and myeloid leukocyte differentiation. Acts upstream of or within cellular response to interleukin-4; epithelial cell development; and fatty acid biosynthetic process. Located in glycogen granule. Is expressed in several structures, including adipose tissue; alimentary system; integumental system; nervous system; and sensory organ. Orthologous to human FASN (fatty acid synthase). PHENOTYPE: Targeted mutation of this locus has implicated its product in embryogenesis as all homozygotes and most heterozygotes die prior to birth. [provided by MGI curators] |