Primary Identifier | MGI:1920929 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 73679 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables piRNA binding activity. Involved in meiotic nuclear division; spermatogenesis; and transposable element silencing. Acts upstream of or within several processes, including homologous chromosome pairing at meiosis; male gonad development; and spongiotrophoblast cell proliferation. Located in cytoplasm and nucleus. Is expressed in several structures, including blastocyst; brain; early embryo; gonad; and tooth. Orthologous to human TEX19 (testis expressed 19). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased fertility, which in males is due to impaired spermatogenesis and increased male germ cell apoptosis. [provided by MGI curators] |