| Primary Identifier | MGI:1916087 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 68837 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including intracellular glucose homeostasis; negative regulation of autophagy; and regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in several structures, including blastocyst; nervous system; reproductive system; and urinary system. Orthologous to human FOXK2 (forkhead box K2). PHENOTYPE: Mice homozygous for a null allele exhibit decreased body weight, reduced circulating lactate level, abnormal glucose homeostasis, and decreased glucose uptake in several tissues, including kidney, lung and muscle. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
