Primary Identifier | MGI:107949 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 11852 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GDP binding activity. Involved in several processes, including positive regulation of angiogenesis; positive regulation of apoptotic process; and regulation of modification of postsynaptic structure. Acts upstream of or within intracellular protein transport. Located in endosome; nucleus; and plasma membrane. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including branchial arch; central nervous system; embryo ectoderm; heart; and sensory organ. Orthologous to human RHOB (ras homolog family member B). PHENOTYPE: Homozygous mutation of this gene results in increased incidence of DMBA-induced skin tumors. [provided by MGI curators] |