Primary Identifier | MGI:1931751 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 80913 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lncRNA binding activity and pumilio-response element binding activity. Involved in several processes, including adipose tissue development; hair follicle development; and respiratory electron transport chain. Acts upstream of or within post-transcriptional regulation of gene expression and stress granule assembly. Located in cytoplasmic stress granule. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and immune system. Orthologous to human PUM2 (pumilio RNA binding family member 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit significantly smaller testes and seminiferous tubule degeneration but are otherwise viable and fertile. [provided by MGI curators] |