| Primary Identifier | MGI:96397 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 15902 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription regulator inhibitor activity. Involved in several processes, including digestive tract morphogenesis; mammary gland epithelium development; and regulation of gene expression. Acts upstream of with a negative effect on regulation of gene expression; regulation of neural precursor cell proliferation; and regulation of neuron differentiation. Acts upstream of or within several processes, including hemopoiesis; nervous system development; and regulation of cell development. Located in cytoplasm; euchromatin; and nucleus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; limb; sensory organ; and urinary system. Orthologous to human ID2 (inhibitor of DNA binding 2). PHENOTYPE: Mice homozygous for disruptions in this gene display postnatal lethality with immune system defects. Homozygotes may also have defects in the digestive tract, kidneys, adipose tissue and in mammary gland development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
