Primary Identifier | MGI:1929628 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 58185 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 4 iron, 4 sulfur cluster binding activity. Involved in several processes, including defense response to virus; negative regulation of viral genome replication; and positive regulation of immune response. Located in endoplasmic reticulum and lipid droplet. Is expressed in liver. Human ortholog(s) of this gene implicated in respiratory syncytial virus infectious disease. Orthologous to human RSAD2 (radical S-adenosyl methionine domain containing 2). PHENOTYPE: Mice homozygous for a null allele exhibit impaired T-helper 2 differentitation. [provided by MGI curators] |