| Primary Identifier | MGI:2387176 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 211986 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Acts upstream of or within eating behavior and energy homeostasis. Located in nuclear membrane. Is expressed in lower jaw and submandibular gland primordium. Orthologous to human TMEM18 (transmembrane protein 18). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a male-specific increase in body weight, fat mass and lean mass whether fed standard chow or a high-fat diet, increased suseptibility to diet-induced obesity, increased energy expenditure and increased food intake. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
