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Protein Coding Gene : Sh3yl1 Sh3 domain YSC-like 1

Primary Identifier  MGI:1346118 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  24057
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable phosphatase binding activity and phosphatidylinositol binding activity. Acts upstream of or within phosphatidylinositol biosynthetic process and regulation of ruffle assembly. Predicted to be active in ruffle membrane. Orthologous to human SH3YL1 (SH3 and SYLF domain containing 1).
PHENOTYPE: Homozygous knockout suppresses inflammatory reactions and reduces susceptibility to LPS-induced acute kidney disease. [provided by MGI curators]
  • synonyms:
  • AI314953,
  • Sh3 domain YSC-like 1,
  • YSC84,
  • Ray,
  • Sh3yl1,
  • expressed sequence AI314953,
  • MGI:2144784

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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