Primary Identifier | MGI:1920260 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 73010 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to be active in plasma membrane. Is expressed in adrenal gland; gut; heart; and nervous system. Orthologous to human GPR22 (G protein-coupled receptor 22). PHENOTYPE: Mice homozygous for a null allele exhibit increased response to aortic banding including decreased fractional shortening and decompensated heart failure. [provided by MGI curators] |