| Primary Identifier | MGI:1931221 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 79221 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor binding activity; histone deacetylase activity, hydrolytic mechanism; and transcription corepressor activity. Involved in negative regulation of gene expression, epigenetic. Acts upstream of or within several processes, including determination of adult lifespan; negative regulation of transcription by RNA polymerase II; and regulation of myotube differentiation. Part of histone methyltransferase complex. Is expressed in several structures, including 2-cell stage embryo; heart; musculoskeletal system; nervous system; and trunk myotome. Orthologous to human HDAC9 (histone deacetylase 9). PHENOTYPE: Mice homozygous for disruptions in this gene display age dependent cardiac hypertrophy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
