Primary Identifier | MGI:99437 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 11861 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity. Acts upstream of or within brown fat cell differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; jaw bone; paraxial mesenchyme; skeletal musculature; and testis. Orthologous to human ARL4A (ARF like GTPase 4A). PHENOTYPE: Homozygous mutation of this gene results in small testes, reduced sperm count, and abnormal spermiogenesis. Both male and female homozygotes are fertile. [provided by MGI curators] |