Primary Identifier | MGI:1924233 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 76983 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable syntaxin binding activity. Predicted to be involved in several processes, including Golgi vesicle transport; negative regulation of autophagosome assembly; and regulation of ER to Golgi vesicle-mediated transport. Predicted to be located in Golgi-associated vesicle and cis-Golgi network. Predicted to be active in Golgi membrane. Is expressed in vertebral axis musculature. Orthologous to human SCFD1 (sec1 family domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, some blastocysts fail to hatch from the zona pellucida and do not form outgrowths while others do hatch but form outgrowths with no inner cell mass and dispersed trophectoderm. [provided by MGI curators] |