Primary Identifier | MGI:2151064 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 94186 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including armadillo repeat domain binding activity; calmodulin binding activity; and enzyme binding activity. Predicted to be involved in negative regulation of intracellular signal transduction; regulation of transcription by RNA polymerase II; and response to estradiol. Is active in postsynapse. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system. Orthologous to human STRN3 (striatin 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, absent primitive node and head folds, failure to gastrulate, and complete lethality between implantation and placentation. [provided by MGI curators] |