Primary Identifier | MGI:1931050 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 56784 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity and protein heterodimerization activity. Acts upstream of with a negative effect on negative regulation of DNA-binding transcription factor activity. Located in cytoplasm and nucleus. Is expressed in several structures, including 1st branchial arch; brain; metanephros; placenta; and trunk. Orthologous to human RALGAPA1 (Ral GTPase activating protein catalytic subunit alpha 1). PHENOTYPE: Mice homozygous for a conditional allele activated in muscle cells exhibit improved glucose and lipid control. [provided by MGI curators] |