Primary Identifier | MGI:106207 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 17420 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and metal ion binding activity. Acts upstream of or within several processes, including adult heart development; response to calcium ion; and ventricular system development. Predicted to be located in nucleoplasm. Predicted to be part of CAK-ERCC2 complex; RNA polymerase II transcription regulator complex; and cyclin-dependent protein kinase holoenzyme complex. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and hemolymphoid system gland. Orthologous to human MNAT1 (MNAT1 component of CDK activating kinase). PHENOTYPE: Mice homozygous for disruption of this gene die as embryos at some point between implantation and gastrulation. [provided by MGI curators] |