| Primary Identifier | MGI:96243 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 15512 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycolipid binding activity. Involved in positive regulation of ATPase-coupled calcium transmembrane transporter activity and spermatogenesis. Acts upstream of or within several processes, including male meiosis I; positive regulation of G2/M transition of mitotic cell cycle; and synaptonemal complex disassembly. Located in cell surface; meiotic spindle; and nucleus. Part of CatSper complex. Is expressed in several structures, including 2-cell stage embryo; alimentary system; ganglia; medulla oblongata basal plate; and submandibular gland primordium. Orthologous to human HSPA2 (heat shock protein family A (Hsp70) member 2). PHENOTYPE: Homozygotes for a targeted null mutation exhibit male sterility associated with lack of postmeiotic germ cells and markedly increased frequency of spermatocyte apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
