Primary Identifier | MGI:107946 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 12192 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including 3'-UTR-mediated mRNA destabilization; cellular response to cAMP; and cellular response to raffinose. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and post-transcriptional regulation of gene expression. Located in cytoplasm and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human ZFP36L1 (ZFP36 ring finger protein like 1). PHENOTYPE: Homozygous null mice display embryonic lethality with failure of chorioallantoic fusion. [provided by MGI curators] |