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Protein Coding Gene : Mideas mitotic deacetylase associated SANT domain protein

Primary Identifier  MGI:2685106 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  238317
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable transcription corepressor activity. Predicted to be involved in chromatin organization; negative regulation of DNA-templated transcription; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of histone deacetylase complex and transcription regulator complex. Is expressed in brain; cerebral cortex; and telencephalon ventricular layer. Orthologous to human MIDEAS (mitotic deacetylase associated SANT domain protein).
PHENOTYPE: Homozygous knockout affects mitosis and hematopoiesis (embryos lack red blood cells) and is embryonic lethal. [provided by MGI curators]
  • synonyms:
  • mitotic deacetylase associated SANT domain protein,
  • MGI:1924593,
  • gene model 260, (NCBI),
  • Gm260,
  • Mideas,
  • 9430029N19Rik,
  • MGI:6391254,
  • C130039O16Rik,
  • Elmsan1,
  • RIKEN cDNA 9430029N19 gene,
  • RIKEN cDNA C130039O16 gene,
  • ELM2 and Myb/SANT-like domain containing 1

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Genome

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1 Involved In Mutations

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