Primary Identifier | MGI:2685106 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 238317 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of histone deacetylase complex and transcription regulator complex. Is expressed in brain; cerebral cortex; and telencephalon ventricular layer. Orthologous to human MIDEAS (mitotic deacetylase associated SANT domain protein). PHENOTYPE: Homozygous knockout affects mitosis and hematopoiesis (embryos lack red blood cells) and is embryonic lethal. [provided by MGI curators] |