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Protein Coding Gene : Bbof1 basal body orientation factor 1
Primary Identifier  MGI:1920123 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  72873
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in sperm axoneme assembly. Acts upstream of or within several processes, including cilium movement involved in cell motility; negative regulation of microtubule depolymerization; and protein stabilization. Located in axoneme and sperm flagellum. Orthologous to human BBOF1 (basal body orientation factor 1).
PHENOTYPE: Mice homozygous for a null allele exhibit male sterility, asthenozoospermia, and abnormal sperm flagellum morphology and function. [provided by MGI curators]
  • synonyms:
  • Ccdc176,
  • AI427784,
  • MGI:2144815,
  • 2900006K08Rik,
  • basal body orientation factor 1,
  • coiled-coil domain containing 176,
  • expressed sequence AI427784,
  • RIKEN cDNA 2900006K08 gene,
  • Bbof1
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1 Involved In Mutations

Trail: ProteinCodingGene

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