Primary Identifier | MGI:3588197 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 432677 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleus. Orthologous to human VRTN (vertebrae development associated). PHENOTYPE: Mice homozygous for a null allele exhibit delayed embryonic development, impaires somite formation, failure to initate turning and lethality between E10.5 and E11.5. Mice heterozygous for the allele exhibit kyphosis, decreased thoracic vertebrae numbers and missing rib. [provided by MGI curators] |