Primary Identifier | MGI:1924183 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 76933 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and molecular adaptor activity. Acts upstream of or within response to virus. Predicted to be located in nuclear envelope. Predicted to be active in mitochondrial membrane. Is expressed in embryo. Orthologous to several human genes including IFI27L2 (interferon alpha inducible protein 27 like 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal susceptibility to infection with H1N1 or H7N7 influenza A virus, although sloughing of dead cells into bronchiolar lumen persists somewhat longer after infection than in infected controls. [provided by MGI curators] |